Scientific Evidence

Systems biology approaches in cancer pathology

Jan 2018

A method for objective quantification of epithelial and stromal biomarkers to generate a tissue profile aiding predictive models for cancer pathology.

Author: DeWard AD, et al.

Publication: Methods in Molecular Biology

Signatures of field cancerization: a step towards earlier detection of esophageal adenocarcinoma

Aug 2017

Detection of the field effect in the clinical setting with validated, cost-effective diagnostic assays may increase the detection of HGD and EAC.

Author: DeWard AD, et al.

Publication: Translational Cancer Research

Signatures of field cancerization: a step towards earlier detection of esophageal adenocarcinoma

Aug 2017

Detection of the field effect in the clinical setting with validated, cost-effective diagnostic assays may increase the detection of HGD and EAC.

Author: DeWard AD, et al.

Publication: Translational Cancer Research

A tissue systems pathology test detects abnormalities associated with prevalent high-grade dysplasia and esophageal cancer in Barrett’s esophagus

Feb 2017

A tissue systems pathology test may provide an objective method to facilitate earlier therapeutic intervention of Barrett's esophagus patients.

Author: Critchley-Thorne RJ, et al.

Publication: Cancer Epidemiology, Biomarkers & Prevention

A tissue systems pathology assay for high-risk Barrett’s esophagus

Oct 2016

Exploration of a tissue systems pathology approach to predict progression in patients with non-dysplastic Barrett's esophagus.

Author: Critchley-Thorne RJ, et al.

Publication: Cancer Epidemiology, Biomarkers & Prevention

Individualized risk prediction in Barrett’s esophagus

Jul 2016

Barrett’s esophagus management decisions are often based on subjective diagnoses, so better information and techniques are needed to aid in BE patient care.

Author: DeWard AD, et al.

Publication: Medical Laboratory Observer

Individualized risk prediction in Barrett’s esophagus

Jul 2016

Barrett’s esophagus management decisions are often based on subjective diagnoses, so better information and techniques are needed to aid in BE patient care.

Author: DeWard AD, et al.

Publication: Medical Laboratory Observer

A tissue systems pathology assay for high-risk Barrett’s esophagus

May 2016

Exploration of a tissue systems pathology approach to predict progression in patients with non-dysplastic Barrett's esophagus.

Author: Critchley-Thorne RJ, et al.

Publication: Cancer Epidemiology, Biomarkers & Prevention

A tissue systems pathology test detects a field effect associated with high-grade dysplasia and esophageal cancer in Barrett’s esophagus patients

May 2016

TissueCypher better predicts the presence of HGD and EAC in BE than pathologic variables and can improve histology to identify patients requiring therapy.

Author: Critchley-Thorne RJ, et al.

Publication: Poster presentation (Sa1257) at DDW 2016, San Diego

A cost-effectiveness analysis of a test that predicts risk of malignant progression in Barrett’s esophagus

May 2016

TissueCypher is cost-saving after five years and improves patient outcomes due to improving the effectiveness of surveillance and treatment.

Author: Hao J, et al.

Publication: Podium presentation (CN4) at ISPOR 2016, Washington DC

A tissue systems pathology test detects a field effect associated with high grade dysplasia and esophageal cancer in Barrett’s esophagus patients

May 2016

TissueCypher better predicts presence of HGD and EAC in BE than pathologic variables, and can improve on histology to identify patients requiring therapy.

Author: Critchley-Thorne RJ, et al.

Publication: Poster presentation (Sa1257) at DDW 2016, San Diego

A cost-effectiveness analysis of a test that predicts risk of malignant progression in Barrett’s esophagus

May 2016

TissueCypher is cost-saving after five years and improves patient outcomes due to improving the effectiveness of surveillance and treatment.

Author: Hao J, et al.

Publication: Podium presentation (CN4) at ISPOR 2016, Washington DC