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Gene Expression Profiling Prognostication of Posterior Uveal Melanoma: Does Size Matter?

June 1, 2020
DecisionDx-UM
Authors: Binkley EM, Bena JF, Davanzo JM, Hinz C, Boldt HC, Singh AD
Prognostic
Ophthalmology

Prospective evaluation of risk-appropriate management of uveal melanoma patients informed by gene expression profiling. Melanoma Manag 2020;7(1):MMT37.

March 11, 2020
DecisionDx-UM
Authors: Schefler AC, Skalet A, Oliver SCN, et al.
Prognostic
Ophthalmology

Gene expression profiling and PRAME status versus tumor-node-metastasis staging for prognostication in uveal melanoma. Am J Ophthalmol 2018;195:154–60.

November 1, 2019
DecisionDx-UM
Authors: Cai L, Paez-Escamilla M, Walter SD, et al.
Prognostic
Ophthalmology

A Cost-Effectiveness Analysis of an Adenocarcinoma Risk Prediction Multi-Biomarker Assay for Patients with Barrett’s Esophagus

October 25, 2019
The TissueCypher assay would be cost-effective after 5 years and improves patient outcomes by improving effectiveness of surveillance and treatment protocols.
TissueCypher
Barrett's Esophagus
Prognostic
Gastroenterology
Publication

Next-generation sequencing of uveal melanoma for detection of genetic alterations predicting metastasis.

April 1, 2019
DecisionDx-UM
Authors: Afshar AR, Damato BE, Stewart JM, et al.
Prognostic
Ophthalmology

Barrett’s Esophagus Panel: Predicting Progression in Barrett’s Esophagus Recent Advances Webinar

November 28, 2018
A panel discussion on the clinical challenges associated with predicting progression to esophageal adenocarcinoma in patients with Barrett’s esophagus.
TissueCypher
Barrett's Esophagus
Authors: Sri Komanduri, MD, FASGE, AGAF Director of Endoscopy Northwestern University, David Diehl, MD, FACP, FASGE Director of Interventional Endoscopy Geisinger Health System, Prasad G. Iyer, MD, MS, FASGE, FACG, Gastroenterologist, Mayo Clinic,
Prognostic
Gastroenterology
Webinar

Do largest basal tumor diameter and the American Joint Committee on Cancer’s cancer staging influence prognostication by gene expression profiling in choroidal melanoma. Am J Ophthalmol 2018 Nov;195:83–92.

November 1, 2018
DecisionDx-UM
Authors: Demirci H, Niziol LM, Ozkurt Z, Slimani N, Ozgonul C, Liu T, et al.
Prognostic
Ophthalmology

Gene expression profiling in uveal melanoma: technical reliability and correlation of molecular class with pathologic characteristics. Diagn Pathol 2017;12(1):59.

March 1, 2017
DecisionDx-UM
Authors: Plasseraud KM, Wilkinson JK, Oelschlager KM, et al.
Prognostic
Ophthalmology

A Tissue Systems Pathology Test Detects Abnormalities Associated with Prevalent High-Grade Dysplasia and Esophageal Cancer in Barrett’s Esophagus

February 5, 2017
A tissue systems pathology test may provide an objective method to facilitate earlier therapeutic intervention of Barrett's esophagus patients.
TissueCypher
Barrett's Esophagus
Authors: Rebecca J. Critchley-Thorne
Prognostic
Gastroenterology
Publication

Signatures of Field Cancerization: A Step Towards Earlier Detection of Esophageal Adenocarcinoma

January 1, 2017
Detection of the field effect in the clinical setting with validated, cost-effective diagnostic assays may increase the detection of HGD and EAC.
TissueCypher
Barrett's Esophagus
Authors: Aaron DeWard
Prognostic
Gastroenterology
Publication

Epigenetic reprogramming and aberrant expression of PRAME are associated with increased metastatic risk in Class 1 and 2 uveal melanomas. Oncotarget 2016;7(37): 59209-19.

September 13, 2016
DecisionDx-UM
Authors: Field MG, Durante MA, Decatur CL, et al.
Prognostic
Ophthalmology

Individualized Risk Prediction in Barrett’s Esophagus

July 20, 2016
Barrett’s esophagus management decisions are often based on subjective diagnoses, so better information and techniques are needed to aid in BE patient care
TissueCypher
Barrett's Esophagus
Authors: Aaron DeWard
Prognostic
Gastroenterology
Publication